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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C2HBrClF3
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RX_link
http://www.rxlist.com/cgi/generic2/halothane.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Suckling, Raventos, U.S. pat. 2,921,098 (1960 to I.C.I.); Scherer, Kuhn, U.S. pat. 2,959,624 (1960 to Hoechst)
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Molecular Weight
197.381 g/mol
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Melting Point
-118 oC
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H2O Solubility
3.45 mg/ml
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State
Liquid
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LogP
2.549
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Dosage Forms
Solution
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Indication
For the induction and maintenance of general anesthesia
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Pharmacology
Halothane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It reduces the blood pressure and frequently decreases the pulse rate and depresses respiration. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
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Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
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Organisms Affected
Humans and other mammals